The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions
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چکیده
منابع مشابه
The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions.
INTRODUCTION The in vivo fate and effectiveness of a drug depends highly on its absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Organic anion transporting polypeptides (OATPs) are membrane proteins involved in the cellular uptake of various organic compounds, including clinically used drugs. Since OATPs are significant players in drug absorption and distribution, modula...
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ژورنال
عنوان ژورنال: Expert Opinion on Drug Metabolism & Toxicology
سال: 2016
ISSN: 1742-5255,1744-7607
DOI: 10.1080/17425255.2017.1253679